FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Wang Theodore T
2. Date of Event Requiring Statement (Month/Day/Year)
09/11/2017
3. Issuer Name and Ticker or Trading Symbol
EKSO BIONICS HOLDINGS, INC. [EKSO]
(Last)
(First)
(Middle)
C/O EKSO BIONICS HOLDINGS, INC., 1414 HARBOUR WAY SOUTH, SUITE 1201
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

RICHMOND, CA 94804
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 20,534,898
I (1)
By Puissance Cross-Border Opportunities II LLC

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (right to buy)   (2) 09/19/2027 Common Stock 37,500 $ 1.15 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Wang Theodore T
C/O EKSO BIONICS HOLDINGS, INC.
1414 HARBOUR WAY SOUTH, SUITE 1201
RICHMOND, CA 94804
  X   X    
Puissance Cross-Border Opportunities II LLC
C/O PUISSANCE CAPITAL FUND (GP) LLC
950 THIRD AVENUE, 25TH FLOOR
NEW YORK, NY 10022
    X    
Puissance Capital Fund (GP) LLC
950 THIRD AVENUE, 25TH FLOOR
NEW YORK, NY 10022
    X    
Puissance Capital Management LP
950 THIRD AVENUE, 25TH FLOOR
NEW YORK, NY 10022
    X    
Puissance Capital Management (GP) LLC
950 THIRD AVENUE, 25TH FLOOR
NEW YORK, NY 10022
    X    

Signatures

Theodore T. Wang 09/25/2017
**Signature of Reporting Person Date

Puissance Cross-Border Opportunities II LLC, By: Puissance Capital Fund (GP) LLC, its general partner, By: Theodore T. Wang, Managing Member 09/25/2017
**Signature of Reporting Person Date

Puissance Capital Fund (GP) LLC, By: Theodore T. Wang, Managing Member 09/25/2017
**Signature of Reporting Person Date

Puissance Capital Management LP, By: Puissance Capital Management (GP) LLC, its general partner, By: Theodore T. Wang, Managing Member 09/25/2017
**Signature of Reporting Person Date

Puissance Capital Management (GP) LLC, By: Theodore Wang, Managing Member 09/25/2017
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These securities are held directly by Puissance Cross-Border Opportunities II LLC and may be deemed to be beneficially owned by Puissance Capital Management LP, the investment manager of Puissance Cross Border Opportunities II LLC; Puissance Capital Management (GP) LLC, the general partner of Puissance Capital Management LP; Puissance Capital Fund (GP) LLC, the general partner of Puissance Cross Border Opportunities II LLC; and Theodore T. Wang, the managing member of Puissance Capital Management (GP) LLC and Puissance Capital Fund (GP) LLC. The Reporting Persons each disclaim beneficial ownership of the reported securities except to the extent of its pecuniary interest therein. This report shall not be deemed an admission that any Reporting Person is the beneficial owner of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.
(2) On September 19, 2017, Theodore T. Wang was granted an option to purchase 37,500 shares of common stock in connection with his appointment to the Board of Directors of the issuer on the same date. The option vests in four equal annual installments beginning on the first anniversary of the date of grant.

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