Annual report pursuant to Section 13 and 15(d)

Income Taxes - Narrative (Details)

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Income Taxes - Narrative (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Increase (decrease) in valuation allowance $ (5,608) $ 4,153
Remeasurement of deferred tax assets 17,220  
Federal    
Operating loss carryforwards 142,076  
Federal | Options to purchase common stock    
Deferred Tax Assets, Net of Valuation Allowance 1,749  
Federal | Research and Development Tax Credit    
Operating loss carryforwards 1,776  
State    
Operating loss carryforwards 87,803  
State | Options to purchase common stock    
Deferred Tax Assets, Net of Valuation Allowance 689  
State | Research and Development Tax Credit    
Operating loss carryforwards 738  
Foreign    
Operating loss carryforwards 7,537  
Generated Before 2018, Expire 2027 | Federal    
Operating loss carryforwards 120,792  
Generated Before 2018, Carryforward Indefinitely | Federal    
Operating loss carryforwards $ 21,284