Annual report pursuant to Section 13 and 15(d)

Summary of Significant Accounting Policies and Estimates (Details 1)

v3.3.1.900
Summary of Significant Accounting Policies and Estimates (Details 1) - shares
shares in Thousands
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities 40,619 24,587 8,944
Options to purchase common stock [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities 13,743 10,791 7,555
Warrants for common stock [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities 13,745 13,796 1,389
Common stock issuable upon conversion of preferred shares [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities 13,131 0 0