Annual report pursuant to Section 13 and 15(d)

Capitalization and Equity Structure (Details Textual)

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Capitalization and Equity Structure (Details Textual) - USD ($)
$ / shares in Units, $ in Thousands
 1 Months Ended 12 Months Ended
Aug. 17, 2016
Aug. 12, 2016
Oct. 30, 2017
Aug. 31, 2017
Apr. 30, 2017
Aug. 31, 2016
Dec. 31, 2015
Dec. 23, 2015
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Sep. 30, 2017
Jan. 15, 2014
Class of Stock [Line Items]                          
Common Stock, Shares Authorized     70,000,000           141,429,000 [1] 141,429,000 [1]      
Preferred Stock, Shares Authorized                 10,000,000 10,000,000      
Common Stock, Shares, Issued                 59,943,000 21,894,000      
Common Stock, Shares, Outstanding                 59,943,000 21,894,000      
Preferred Stock, Shares Issued               15,000 0 0      
Preferred Stock, Shares Outstanding                 0 0      
Class of Warrant or Right, Number of Securities Called by Warrants or Rights               2,122,000          
Gross Proceeds from Preferred Stock and Warrants               $ 15,000          
Proceeds from Issuance of Preferred Stock, Preference Stock, and Warrants, Total               13,906 $ 0 $ 0 $ 13,906    
Stock Related Expenses Payable               $ 173          
Preferred Stock Converted Into Common stock               3,300,000     2,000    
Payments of Stock Issuance Costs                 0 $ 173 $ 0    
Amortization of Financing Costs and Discounts, Total                     1,355    
Warrants Not Settleable in Cash, Fair Value Disclosure                 11,700        
Conversion of Stock, Shares Issued           267   141   1,389,000      
Proceeds from Issuance of Common Stock                 $ 42,463 $ 14,694 $ 0    
Preferred Stock Convertible Conversion Price                   $ 7.07 $ 7.07    
Conversion of Stock, Shares Converted                 921,000        
Stockholders' Equity, Reverse Stock Split [2]                 1-for-7 reverse        
Common Stock, Par or Stated Value Per Share                 $ 0.001 $ 0.001      
Class Of Warrant Or Right Issued                 2,066,000        
Stock Issued During Period, Value, New Issues       $ 34,000         $ 11,058 $ 14,694 $ 14,218    
Shares Issued, Price Per Share       $ 1.00                  
Issuance of Stock and Warrants for Services or Claims       $ 131                  
Shares Subscription, Description       1.1608                  
Stock Issued During Period, Reverse Stock Splits, Description     On October 30, 2017, the Board approved an amendment to the Company’s Articles of Incorporation to increase the number of shares of our common stock by 70,000 shares to 141,429 shares (the “Authorized Capital Amendment”), subject to the approval of such amendment by the stockholders. On December 21, 2017, a special meeting of the stockholders was convened (the “December Special Meeting”). In the definitive proxy statement dated November 24, 2017 filed by us with the SEC in respect of the December Special Meeting (the “November Proxy Statement”), the Board solicited the vote of the stockholders in favor of the Authorized Capital Amendment. The November Proxy Statement stated that broker non-votes in respect of the Authorized Capital Amendment would be counted as votes against the amendment. However, under relevant stock exchange rules, brokers had the discretionary authority to vote any shares held in their name on behalf of a beneficial owner (“Broker Shares”), and in respect of which the broker did not receive voting instruction from the beneficial owner, in favor of the Authorized Capital Amendment. As such, brokers voted approximately 17,628 Broker Shares, in respect of which the brokers had not received voting instructions from the beneficial owners of such shares, in favor of the Authorized Capital Amendment at the December Special Meeting. Accordingly, after taking into account such Broker Shares, the Authorized Capital Amendment was approved by the stockholders at the December Special Meeting. However, as disclosed in more detail under Item 3 to this Annual Report on Form 10-K, some stockholders of the Company have claimed that the disclosure in the November Proxy Statement in connection with the effect on the Authorized Capital Amendment of beneficial owners not providing voting instructions in respect of their Broker Shares was incorrect. Accordingly, stockholders will be asked to vote again on the Authorized Capital Amendment our 2018 Annual Meeting of Shareholders. Further information about such vote will be provided in the Company’s Proxy Statement relating to its 2018 Annual Meeting of Shareholders, to be filed with the SEC within 120 days of December 31, 2017.                    
Payments for Repurchase of Warrants, Per share         $ 1.23                
Puissance Cross-Border Opportunities II LLC [Member]                          
Class of Stock [Line Items]                          
Stock Issued During Period, Shares, New Issues       20,534,898,000                  
Warrant Repurchase Agreement [Member]                          
Class of Stock [Line Items]                          
Repurchase Price Per Share       $ 1.23 1.23                
Number Of Warrant Shares Repurchased       1,866,000                  
Payments for Repurchase of Warrants       $ 2,245                  
Minimum [Member]                          
Class of Stock [Line Items]                          
Preferred Stock Convertible Conversion Price                 $ 3.74        
Maximum [Member]                          
Class of Stock [Line Items]                          
Preferred Stock Convertible Conversion Price                 $ 7.07        
Common Stock, Outstanding, Percentage       40.00%                  
2016 Equity Offering [Member]                          
Class of Stock [Line Items]                          
Conversion of Stock, Shares Issued 267,000                        
Over-Allotment Option [Member]                          
Class of Stock [Line Items]                          
Proceeds from Issuance of Common Stock $ 998                        
Rights Offering [Member]                          
Class of Stock [Line Items]                          
Stock Issued During Period, Shares, New Issues       13,465,000         13,465,000        
Payments of Stock Issuance Costs       $ 286                  
Proceeds from Issuance of Common Stock       13,179         $ 13,179        
Stock Issued During Period, Value, New Issues       13,465                  
Backstop Investor Offering [Member]                          
Class of Stock [Line Items]                          
Stock Issued During Period, Value, New Issues       $ 20,535                  
2017 Warrants [Member]                          
Class of Stock [Line Items]                          
Class of Warrant or Right, Exercise Price of Warrants or Rights         $ 4.10       $ 4.1        
Class Of Warrant Or Right Issued         1,866,000       1,866,000        
2015 Warrants [Member]                          
Class of Stock [Line Items]                          
Class of Warrant or Right, Exercise Price of Warrants or Rights                 $ 3.74        
Class Of Warrant Or Right Issued             2,122,000   0        
Information Agent Warrants [Member]                          
Class of Stock [Line Items]                          
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                       200,000  
Class of Warrant or Right, Exercise Price of Warrants or Rights                 $ 1.5     $ 1.50  
Class Of Warrant Or Right Issued                 200,000        
Warrant [Member]                          
Class of Stock [Line Items]                          
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                         5,151,000
Preferred Shares and Warrants Purchase Price                 $ 487        
Class of Warrant or Right, Exercise Price of Warrants or Rights                         $ 14.00
Payments of Stock Issuance Costs         $ 185                
Warrant [Member] | Minimum [Member]                          
Class of Stock [Line Items]                          
Class of Warrant or Right, Exercise Price of Warrants or Rights             $ 3.74       $ 3.74    
Warrant [Member] | Maximum [Member]                          
Class of Stock [Line Items]                          
Class of Warrant or Right, Exercise Price of Warrants or Rights             $ 8.75       $ 8.75    
Warrant [Member] | Offer to Amend and Exercise [Member]                          
Class of Stock [Line Items]                          
Class of Warrant or Right, Exercise Price of Warrants or Rights                         $ 7.00
Warrant [Member] | Merger and PPO [Member]                          
Class of Stock [Line Items]                          
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                         4,329,000
Common Stock [Member]                          
Class of Stock [Line Items]                          
Stock Issued During Period, Shares, New Issues         3,732,000       3,732,000 4,017,000 0    
Class of Warrant or Right, Number of Securities Called by Warrants or Rights         1,866,000       88,000        
Class of Warrant or Right, Exercise Price of Warrants or Rights                 $ 9.66        
Proceeds from Issuance of Common Stock         $ 10,919                
Common Stock, Par or Stated Value Per Share         $ 0.001                
Stock Issued During Period, Value, New Issues                 $ 4 $ 4 $ 0    
Common Stock [Member] | 2016 Equity Offering [Member]                          
Class of Stock [Line Items]                          
Stock Issued During Period, Shares, New Issues   3,750,000                      
Sale of Stock, Price Per Share   $ 4.00                      
Proceeds from Issuance of Common Stock   $ 13,696                      
Series A Preferred Stock [Member]                          
Class of Stock [Line Items]                          
Conversion of Stock, Shares Issued                   921,000      
Preferred Stock Convertible Conversion Price                   $ 3.74      
Conversion of Stock, Shares Converted                   3,000      
Convertible Preferred Stock [Member]                          
Class of Stock [Line Items]                          
Preferred Stock, Shares Outstanding             13,000       13,000    
Stock Issued During Period, Shares, New Issues                 0 0 15,000    
Amortization of Financing Costs and Discounts, Total                   $ 10,345      
Conversion of Stock, Shares Converted                   10,000      
Stock Issued During Period, Value, New Issues                 $ 0 $ 0 $ 0    
[1] Refer to Note 13, Capitalization and Equity Structure – Summary, for additional information regarding the calculation of the number of common stock shares authorized.
[2] The April 2017 Warrants were repurchased at a price of $1.23 per underlying share, as a result of the August 2017 Rights Offering.